Educational Articles
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Naloxone (brand name Narcan®) is a drug used to reverse the effects of opioids. It is used primarily under direct supervision of a veterinarian. It is used off-label in veterinary medicine. Naloxone comes in nasal spray and injectable forms.
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Nitrofurantoin is an antibiotic used to treat bacterial urinary bladder infections. It is typically used as a second-line antibiotic, when broad-spectrum antibiotics have not cleared the infection. It is used “off label” or “extra label” in veterinary medicine. Nitrofurantoin comes in capsule or liquid forms given orally. Never use in food-producing animals or animals intended for food.
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Nystatin is an antifungal, given by mouth in the form of a tablet or liquid suspension, and used off label to treat Candida fungal infections in dogs, cats, birds, and reptiles. Side effects are rare, but at high doses, it could cause stomach upset or mouth irritation. It should not be used in pets that are allergic to it.
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Olopatadine ophthalmic is an antihistamine medication used to treat pruritus (itchiness) of the eyes caused by allergies in animals. Olopatadine ophthalmic comes in liquid drop suspension form.
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Omeprazole is given by mouth and is used off-label to treat ulcers and erosions in the stomach and upper small intestine. Give as directed. Side effects are uncommon but may include stomach upset, such as vomiting, diarrhea, or gas. Do not use in pets with a history of allergies to this class of drugs. If a negative reaction occurs, call your veterinarian.
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Orbifloxacin is given by mouth and is used on and off label to treat certain susceptible bacterial infections. Give as directed by your veterinarian. The most common side effects include vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other quinolones, in growing pets, or in conjunction with cyclosporine. If a negative reaction occurs, please call your veterinary office.
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Oxytetracycline/polymyxin B ophthalmic (brand name Terramycin®) is a combination antimicrobial medication used to treat certain types of bacteria (gram-positive and gram-negative). It is used to treat eye infections in cats and dogs. It is used “off label” or “extra-label” to treat eye infections in avian species, hedgehogs, and rabbits. Oxytetracycline/polymyxin B comes in ointment form.
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Phenobarbital is given by mouth or as an injection to treat seizures or to sedate your pet. Common side effects include sleepiness, increased thirst, urination, and/or appetite. Do not use this medication in pets with liver, lung, or kidney disease or those that are allergic to barbiturates. If a negative reaction occurs, call your veterinary office.
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Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.
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Praziquantel is given on and off label and by mouth or injection to treat various internal parasites in cats, dogs, small mammals, birds, reptiles, and large animals. Do not use in pets that are allergic to it, in puppies less than 3 weeks old, or kittens less than 6 weeks old.
